Powered by Platelet-Derived Exosomes

Exosomes may be one of beauty's most talked-about innovations, but with (plated) EXOSOME Serum, the science goes considerably deeper.

At the center of the formula are human platelet-derived exosomes, microscopic biological messengers associated with the skin's natural renewal processes. Rooted in regenerative medicine research at the Mayo Clinic Van Cleve program, (plated)'s technology brings a medical research heritage to advanced cosmetic skincare, supported by more than 10 peer-reviewed studies cited by the brand.

The distinction matters. Not all exosomes are created equally.

Unlike the plant-derived and synthetic alternatives commonly found in skincare, (plated) uses exosomes derived from human platelets. These naturally occurring messengers form the foundation of an approach designed to improve the visible quality of skin, addressing the appearance of fine lines, wrinkles, redness, brown spots and uneven texture.

At the heart of the technology is Renewosome™, a proprietary stabilization process that helps maintain the integrity of platelet-derived exosomes outside the clinical environment. The result is a shelf-stable formula that brings this specialized technology into a topical skincare experience.

But the innovation extends beyond exosomes alone.

Formulated specifically for professional, post-procedure care, EXOSOME Serum pairs human platelet extract with hyaluronic acid, hydrolyzed collagen, panthenol and aloe vera. Together, these ingredients deliver hydration, soothing comfort and skin-conditioning benefits, helping skin feel replenished and refreshed.

Unlike (plated)'s retail DAILY Serum, EXOSOME Serum is a specialized 10 mL formulation offered exclusively through select OneSpaWorld onboard Medi-Spas. Recommended and sold by Medi-Spa physicians, it complements professional aesthetic treatments while supporting a more comprehensive approach to visible skin renewal.

The texture is lightweight. The science is anything but.

Why Platelet-Derived Exosomes?

The interesting thing about exosomes is not simply their size. It is their role as biological messengers.

Derived from human platelets, these microscopic structures are associated with the cellular communication processes that support natural renewal. (plated) has developed a proprietary approach to incorporating platelet-derived exosomes into topical skincare, bringing regenerative medicine research into a cosmetic formulation.

Renewosome™ technology plays an essential role, stabilizing the exosomes to help maintain their integrity and enable shelf-stable use.

Rather than focusing on a single visible concern, the technology has been studied for its potential to improve multiple aspects of skin appearance, from fine lines and uneven tone to redness, firmness and radiance.

It is a more comprehensive approach to how skin looks and feels, designed to complement the benefits of professional aesthetic care.

The Science Behind (plated)

Medical research heritage. The technology is rooted in regenerative medicine research at the Mayo Clinic Van Cleve program, bringing a scientific foundation to advanced skincare.

10+ peer-reviewed studies. (plated) cites more than 10 peer-reviewed studies supporting the science behind its platelet-derived exosome technology.

#1 dermatologist-recommended exosome skincare brand. According to (plated), the brand leads its category in dermatologist recommendations.

Human platelet-derived technology. Biologically derived exosomes offer an approach distinct from plant-derived and synthetic alternatives.

Renewosome™ stabilization. Proprietary technology helps stabilize exosomes outside the clinical environment, making topical, shelf-stable use possible.

Physician-led care. Exclusively offered through select OneSpaWorld onboard Medi-Spas, EXOSOME Serum is recommended and sold by physicians as part of a professional skincare experience.

Clinically Studied Benefits

According to clinical and marketing research cited by (plated), its platelet-derived exosome technology has been studied for cosmetic improvements including:

• Softening the appearance of fine lines and wrinkles

• Improving the look of redness and brown spots

• Supporting a more even-looking skin tone and texture

• Improving the appearance of skin firmness

• Promoting healthier, more radiant-looking skin

• Supporting visible improvements in collagen measurements through clinical imaging

Clinical Research

87% improvement in collagen measurement through clinical imaging.¹

¹Based on Masson's trichrome stain in a single subject, an 80-year-old female. Data on file with the manufacturer. This finding should not be interpreted as a typical or guaranteed result.

All clinical and marketing claims are provided by (plated) / the manufacturer, which holds the supporting substantiation. Individual results may vary. (plated) EXOSOME Serum is a cosmetic skincare product.

Key Ingredients in (plated) EXOSOME Serum

Human Platelet Extract

The signature ingredient behind (plated)'s exosome technology. Contains human platelet-derived exosomes associated with visible skin renewal and improvements in the appearance of fine lines, uneven texture and overall skin quality.

Renewosome™ Technology

A proprietary stabilization technology designed to maintain the integrity of platelet-derived exosomes, enabling their use in a shelf-stable topical skincare formula.

Hyaluronic Acid

A moisture-binding ingredient that delivers lasting hydration, helping skin appear plumper, smoother and more supple.

Hydrolyzed Collagen

Helps support the appearance of firmer, smoother skin while complementing the formula's hydrating and conditioning benefits.

Panthenol (Vitamin B5)

A soothing, moisture-attracting ingredient that helps calm and condition skin, leaving it feeling softer and more comfortable.

Aloe Vera

Known for its calming and refreshing properties, aloe vera helps soothe and condition skin, making it especially suited to post-procedure skincare.